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| 1/2/2010 | 9 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Philipsburg, Basseterre, Roseau, St. George's, Scarborough, Bridgetown | 9 |
| 1/11/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 1/22/2010 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 10 |
| 2/1/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 2/12/2010 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 10 |
| 2/22/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 3/5/2010 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 10 |
| 3/15/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 3/26/2010 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 10 |
| 4/5/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 4/16/2010 | 14 Night Westbound Panama Canal Cruise on Millennium | Starting in San Juan with stops in Cartagena, Panama Canal, Puntarenas, Huatulco, Acapulco, Cabo San Lucas, San Diego | 14 |
| 4/30/2010 | 14 Night Ultimate Alaska Cruise on Millennium | Starting in San Diego with stops in Seattle, Sitka, Hubbard Glacier (Cruising), Skagway, Juneau, Icy Strait Point, Tracy Arm Fjord, Ketchikan, Victoria, Vancouver | 14 |
| 5/14/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 5/21/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 5/28/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 6/4/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 6/11/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 6/18/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 6/25/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 7/2/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 7/9/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 7/16/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 7/23/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 7/30/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 8/6/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 8/13/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 8/20/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 8/27/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 9/3/2010 | 7 Night Northbound Alaska Cruise on Millennium | Starting in Vancouver with stops in Inside Passage (Cruising), Ketchikan, Icy Strait Point, Juneau, Skagway, Hubbard Glacier (Cruising), Seward | 7 |
| 9/10/2010 | 7 Night Southbound Alaska Cruise on Millennium | Starting in Seward with stops in Hubbard Glacier (Cruising), Juneau, Skagway, Icy Strait Point, Ketchikan, Inside Passage (Cruising), Vancouver | 7 |
| 9/17/2010 | 10 Night Wine Cruise Cruise on Millennium | Starting in Vancouver with stops in Nanaimo, Victoria, Seattle, San Francisco, Monterey, Catalina Island, San Diego | 10 |
| 9/27/2010 | 14 Night Eastbound Panama Canal Cruise on Millennium | Starting in San Diego with stops in Cabo San Lucas, Acapulco, Huatulco, Puntarenas, Panama Canal, Cristobal Pier, Oranjestad, Willemstad, San Juan | 14 |
| 10/11/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 10/22/2010 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |
| 11/1/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 11/12/2010 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |
| 11/22/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 12/3/2010 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |
| 12/13/2010 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, St. Johns, Roseau, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 12/18/2010 | 15 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Philipsburg, Basseterre, Pointe A Pitre, Roseau, Castries, Bridgetown, Scarborough, St. George's, Willemstad, Oranjestad | 15 |
| 1/3/2011 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 1/14/2011 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |
| 1/24/2011 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 2/4/2011 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |
| 2/14/2011 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 2/25/2011 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |
| 3/7/2011 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 3/18/2011 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |
| 3/28/2011 | 11 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in St. Croix, Basseterre, Roseau, Castries, Bridgetown, St. George's, Willemstad, Oranjestad | 11 |
| 4/8/2011 | 10 Night Southern Caribbean Cruise on Millennium | Starting in San Juan with stops in Tortola, Philipsburg, Castries, Bridgetown, St. George's, Oranjestad, Willemstad | 10 |